TinkerCell

Wiki and Blog

Welcome to the TinkerCell homepage
A computer-aided design (CAD) tool for synthetic biology

Applications: 
  • Biological network design
  • Simulation and other numerical analyses
  • Modules and modular circuit design
  • Synthetic biology (use of biological parts)  
Features: 
  • Customizable hierarchy of biological parts
  • Attributes (e.g. sequence) for characterizing parts
  • Drawing program for designing part graphics
  • Multi-threaded simulations (uses C for speed) 
  • Python scripting
  • Antimony scripts
Functionality: 
  • Deterministic and stochastic simulation
  • Steady state analysis
  • Automatic generation of:
    • Complex reactions with intermediate steps
    • Hill equations for different logical functions
  • Linear programming (lpsolve):
    • Flux balance analysis
  • Integrated PySCeS:
    • Sensitivity analysis
    • Bifurcation analysis
    • Structural analysis 
  • Integrated SciPy:
    • Optimization
    • Statistics
    • Control systems
    • FFT
Interface: 
  • Visual model construction
  • Script-based model construction
  • Programming interface: Python
Extensibility: 
  • Highly flexible C++ plug-in framework
  • C interface
  • Python interface
Availability: 
  • Free
  • Open source
  • Windows, Mac, Linux
Status: 
  • Beta, i.e. works but still fixing bugs
How to join: 
  • Email us (see contacts)
Subpages (1): Cite